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2024年3月19日发(作者：sql数据库恢复工具)

专利内容由知识产权出版社提供

专利名称：MOLECULE-RELEASING APPARATUS AND

MOLECULE-RELEASING METHOD

发明人：TORNOW, Marc,FUJIHARA, Tsuyoshi,FUJITA,

Shozo,TAKEISHI, Shunsaku,ARINAGA,

Kenji,YAMAGUCHI, Yoshitaka,USUKI,

Tatsuya,RANT, Urlich,BUCHHOLZ, Karin

申请号：JP2003007651

申请日：20030617

公开号：WO04/033614P1

公开日：20040422

摘要：It is intended to provide an apparatus for safely releasing molecules and a

method of releasing molecules by which various useful molecules such as DNA can be

efficiently released and migrated toward a subject such as cells and which are applicable

to gene therapy and so on. The molecule-releasing apparatus has a molecule-releasing

means whereby an electrical interaction between molecules with a conductive member

under the application of an electrical potential is relieved by changing the potential so as

to release the molecules from the conductive member. Preferable embodiments of the

apparatus include one wherein the conductive member is provided close to the subject

toward which the molecules are migrated or the conductive member pierces into the

subject, one wherein the conductive member is an electrode, one wherein two or more

conductive members are provided, one wherein the electrode is a needle electrode, one

wherein molecules can be released at different timings by the molecule-releasing means,

one wherein molecules are selected from among ionic polymers, etc. In the molecule-

releasing method, molecules electrically attracted by two or more conductive members

are released at different timings from the conductive members due to electrical

repulsive forces.

申请人：TORNOW, Marc,FUJIHARA, Tsuyoshi,FUJITA, Shozo,TAKEISHI,

Shunsaku,ARINAGA, Kenji,YAMAGUCHI, Yoshitaka,USUKI, Tatsuya,RANT,

Urlich,BUCHHOLZ, Karin

地址：JP,DE,JP,JP,JP,JP,JP,JP,DE,DE

国籍：JP,DE,JP,JP,JP,JP,JP,JP,DE,DE

代理机构：HIROTA, Koichi

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