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2024年12月27日发(作者：安装mysql提示check报错)

硼酸亲和液相层析英文

The English term for "硼酸亲和液相层析" is "boronate

affinity liquid chromatography." Boronate affinity liquid

chromatography is a separation technique that utilizes the

specific reversible interaction between boronic acid and

cis-diol-containing compounds, such as sugars, nucleotides,

and glycoproteins, to separate and analyze these compounds

in a liquid chromatography system. This technique is widely

used in the analysis of glycoproteins and glycopeptides in

biological samples due to its high selectivity and

sensitivity. It is an important tool in the field of

biochemistry, biotechnology, and pharmaceutical analysis.

The principle of boronate affinity liquid chromatography

lies in the reversible covalent binding of cis-diol-

containing compounds to boronic acid-functionalized

stationary phases, allowing for their selective retention

and subsequent elution based on their affinity interactions.

This technique has contributed significantly to the

advancement of glycoprotein and glycopeptide analysis,

particularly in the study of protein glycosylation patterns

and their biological significance. Overall, boronate

affinity liquid chromatography plays a crucial role in the

comprehensive analysis of complex biological samples and

has become an indispensable tool in modern analytical

chemistry.


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