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2024年12月28日发(作者:织梦源码部署)
专利内容由知识产权出版社提供
专利名称:Buffer compensation in enzyme - modified
ion sensitive devices
发明人:Eddowes, Mark James
申请号:EP86309003.1
申请日:19861118
公开号:EP0223597A2
公开日:19870527
专利附图:
摘要:A system suitable for determining the concentration of an enzyme's substrate
in a solution (21) containing a buffer comprises two ion-sensitive devices (22, 23), such as
ISFETS, in contact with the solution, one of the devices (23), e.g. an ENFET, having a layer
(24) containing an enzyme, the enzyme producing ions from its substrate, and the system
comparing the responses of the two devices and providing a control signal to consume
ions as they are generated at the ENFET, or to produce an equal concentration of ions at
the other device, such that the concentrations sensed by each are equal. The signal gives
an indication of the concentration of the substrate. Other ion-sensitive devices may be
used. The concentration of other substances can be determined, for example a device
with an enzyme's substrate can be used for detecting the concentration of an enzyme.
申请人:THORN EMI plc
地址:THORN EMI House Upper Saint Martin's Lane London, WC2H 9ED GB
国籍:GB
代理机构:Fleming, Ian Alexander
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