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2024年12月28日发(作者:织梦源码部署)

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专利名称:Buffer compensation in enzyme - modified

ion sensitive devices

发明人:Eddowes, Mark James

申请号:EP86309003.1

申请日:19861118

公开号:EP0223597A2

公开日:19870527

专利附图:

摘要:A system suitable for determining the concentration of an enzyme's substrate

in a solution (21) containing a buffer comprises two ion-sensitive devices (22, 23), such as

ISFETS, in contact with the solution, one of the devices (23), e.g. an ENFET, having a layer

(24) containing an enzyme, the enzyme producing ions from its substrate, and the system

comparing the responses of the two devices and providing a control signal to consume

ions as they are generated at the ENFET, or to produce an equal concentration of ions at

the other device, such that the concentrations sensed by each are equal. The signal gives

an indication of the concentration of the substrate. Other ion-sensitive devices may be

used. The concentration of other substances can be determined, for example a device

with an enzyme's substrate can be used for detecting the concentration of an enzyme.

申请人:THORN EMI plc

地址:THORN EMI House Upper Saint Martin's Lane London, WC2H 9ED GB

国籍:GB

代理机构:Fleming, Ian Alexander

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